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Diagnosis and Treatment of Dyssynergic Defecation. Jun 28, 2016 Etiology/Pathophysiology. The etiology of dyssynergic defecation is unclear. In a prospective survey of 118 patients with dyssynergia, we found that the problem began during childhood in 31% of patients, and after a particular event, such as pregnancy, trauma, or back injury in 29% of patients, and there was no cause in 40% of ...